Skip Navigation


Journal of Public Health Advance Access originally published online on August 3, 2007
Journal of Public Health 2007 29(4):379-387; doi:10.1093/pubmed/fdm045
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
29/4/379    most recent
fdm045v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (4)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by McCluskey, S.
Right arrow Articles by Middleton, E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by McCluskey, S.
Right arrow Articles by Middleton, E.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The Author 2007, Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved

Reductions in cardiovascular risk in association with population screening: a 10-year longitudinal study



S. McCluskey, Research Fellow1,

D. Baker, Professor1

D. Percy, Senior Lecturer2

P. Lewis, Consultant Cardiologist3

E. Middleton, Research Fellow1
1 Centre for Public Health Research, University of Salford, C701 Allerton Building, Frederick Road Campus, Salford M6 6PU, UK
2 Centre for Operational Research and Applied Statistics, University of Salford, Salford M5 4WT, UK
3 Stockport Acute NHS Trust, Stockport, UK

Address correspondence to Serena McCluskey, E-mail: s.mccluskey{at}salford.ac.uk


  Abstract

Background This study was carried out in order to examine changes in cardiovascular risk associated with a population-based screening programme.

Method Cardiovascular disease (CVD) risk factor data from a representative sample of residents aged between 45 and 55 years who attended screening a total of three times over a 10-year period were chosen for analysis (n = 4113). Cohorts were defined as either ‘high risk’ or ‘normal risk’ at baseline for risk factors including blood pressure, body mass index (BMI), cholesterol, smoking and alcohol intake. Mean changes were observed for both groups over three screening episodes, and results were stratified by gender.

Results For the high-risk cohorts (after controlling for age and regression to the mean effects), there were significant decreases in all risk factors, except BMI. Conversely, the observed changes in the normal risk cohorts indicated significant increases in risk factors over the 10-year period. After adjusting for age, the pattern in the normal risk cohorts fluctuated and there were some decreases in risk, but they were not as large as the decreases in risk for the high-risk cohorts.

Conclusions Population screening for CVD is an effective strategy for identifying and reducing risk in high-risk individuals. These results have significant implications for the role of screening in preventing and controlling cardiovascular disease.

Keywords: cardiovascular disease, epidemiology, screening


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.